Home > Articles & Studies > Supplement Information (General) > SAMe Article


SAMe Information

SAMe (s-adenosylmethionine) is a naturally occurring longevity nutrient that can be produced by the body. It may also be chemically manufactured. As with other substances in the body, aging results in a natural production decline. Discovered in 1953, SAMe is a precursor to the substances spermidine and spermine. It is manufactured in the body from the amino acid methionine. Due to its inherently unstable structure, SAMe is not found in significant quantities from dietary sources. Therefore, SAMe must be obtained through supplementation.

SAMe is a remarkable substance that is utilized by the body in many ways. It has been widely recognized as an effective way to treat osteoarthritis, depression fibromyalgia, and liver conditions. It is used by the body to repair joints, produce neurotransmitters and it has been shown to be as effective as some antidepressant medications. Clinical research has demonstrated that SAMe may be helpful in treating migraine headaches, increasing sperm activity in infertile men, as well as protecting and detoxifying the liver, and maintaining cardiovascular health. It may also serve to inactivate estrogenic compounds.

Populations that may benefit most from the supplementation of SAMe include: persons suffering from arthritis, fibromyalgia, liver conditions, depression or other psychiatric conditions, athletes, and the general population.

Because of the ability of SAMe to treat a host of physical and mental disorders, for persons suffering from such conditions, SAMe, while not a cure, can provide welcome benefit and relief.

Athletes may benefit from SAMe's ability to maintain neurotransmitter balance, liver health and cardiovascular health, as well as its ability to neutralize estrogenic compounds. No studies yet exist to suggest that SAMe can minimize estrogen levels as well as pharmaceutical drugs, but theoretically the minimization of any estrogen may drastically potentate the affects of free testosterone on skeletal musculature.

The general population may benefit from supplementing with SAMe as it plays a key role in maintaining psychological health, and is a longevity nutrient that theoretically will slow physiological hypertrophy associated with aging. Signs of deficiency include rapid aging, arthritis, and depression.

WHAT OUR CUSTOMERS SAY