Nitric Oxide Skeletal Muscle Expander by Physical Sciences Few supplements over the past few years have caused as big of an uproar as nitric oxide (NO) boosters. Initially, these products were all basically just a high dose of the amino acid arginine (arginine being the most abundant nitrogen carrier in humans). With claims of muscle-splitting pumps and bulging veins resembling a roadmap, NO supplements were all the rage in gyms around the world. Enter Physical-Sciences NO Muscle Expander. Packed with more than just arginine, NO Muscle Expander is not just any nitric oxide supplement.
As with any nitric oxide supplement, the primary ingredient in NO Muscle Expander is arginine. However, Physical-Sciences uses L-arginine/L-malate, which is two arginine molecules bonded to a molecule of malic acid. This is a non-polar form of arginine which is rapidly absorbed and used to maintain a positive nitrogen balance in muscles. A positive nitrogen balance is the optimal state the human body can be in in order to build muscle.
For this variation of a nitric oxide supplement, Physical-Sciences has added creatine ethyl ester, or CEE for short. CEE is theoretically a more absorbable form of creatine because it doesn’t require the use of “transporters” to enter cells. Due to the better absorption and longer half-life from the ethyl ester, CEE generally requires smaller doses and works faster while still providing the substantial strength and muscle gains typically associated with creatine monohydrate.
If one form of creatine weren’t enough, NO Muscle Expander also contains creatine phosphate, also known as phosphocreatine. Phosphocreatine plays a major role in ATP production, especially in tissues which require high, fluctuating energy demands such as the muscles and the brain.
Physical-Sciences NO Muscle Expander also contains citrulline malate. Citrulline helps to increase plasma levels and also to extend the life of arginine, therefore prolonging its’ effects such as greater pumps and bulging veins. Citrulline improves aerobic performance and capacity by influencing lactic acid metabolism and reducing fatigue.
To cap off this impressive list of muscle-swelling ingredients, NO Muscle Expander also contains beta-alanine, a naturally occurring beta amino acid. Supplementing with beta-alanine increases the level of carnosine in muscles, thereby decreasing fatigue. Beta-alanine works to maintain pH levels, which is essential for muscles to function properly during intense exercise.
With Physical-Sciences NO Muscle Expander, you get 5 ingredients all working together to promote better pumps, strength gains and better muscular endurance. With a cocktail like that, the only question now is, “What are you waiting for?”
BUILDING BLOCKS SERIES: This series of products will concentrate on providing the user with the highest ratio’s of the highest quality muscle building and enhancing compounds being produced in the world today. Our Nitric Oxide Skeletal Muscle Expander product will focus on Cell volumization, which is the process of increasing a cells volume by changing the internal constitution of the cell during intense physical activity or weight training which results from an increase in the volume of a muscle cell (fibre). Since muscle is approximately 70% water, using nutrients that increase the water and oxygen and nitrogen levels stored in the muscle is obviously going to contribute to it's size and future growth as well as increasing out performance during these times of great physical stress to our skeletal muscular system. We will also be replacing our muscle cells energy as we train for much more effective training sessions and following them. This product is the top choice for individuals demanding optimal performance from their nutritional supplements as they do of themselves.
L-ARGININE L- MALATE: consisting of two molecules of the amino acid arginine bonded to one molecule of malic acid. This non-polar form of arginine is rapidly absorbed in the body and is used to maintain the nitrogen balance in muscles. L-Arginine is a semi-essential amino acid involved in numerous areas of human physiology, including production of nitric oxide (NO)--a key messenger molecule involved in vascular regulation, immune activity, and endocrine function. Arginine is also involved in protein production. Arginine is the most abundant nitrogen carrier in humans, containing four nitrogen atoms per molecule.
CREATINE ETHYL ESTER HCL: Creatine Ethyl Ester- or simply creatine ester,CEE or CE2, is a membrane permeable form of Creatine that theoretically can enter the cells without having to use the “typical” Creatine transporter molecules. It is an ethyl ester derivative of creatine, from which it is made. In the body, CEE is converted back into creatine. Because it is slightly more lipophilic, the ethyl ester allows for easier absorption into the cells, and a longer half-life in the body. Creatine ethyl ester is regarded as an improved version of creatine itself. Advantages of CEE- Works faster and is more efficiently absorbed, Requires smaller dosages, Substantial increase in strength and muscle mass, with none of the gastrointestinal discomfort or water bloating normally associated with the monohydrate form of creatine.
CREATINE PHOSPHATE DISODIUM: is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in skeletal muscle and brain: Phosphocreatine can anaerobically donate a phosphate group to ADP to form ATP during the first 2 to 7 seconds following an intense muscular or neuronal effort. phosphocreatine acts as high-energy reserve in a coupled reaction; the energy given off from donating the phosphate group is used to regenerate the other compound - in this case, ATP. Phosphocreatine plays a particularly important role in tissues that have high, fluctuating energy demands such as muscle and brain.
CITRULLINE MALATE 2:1: is a salt form of the amino acid. The malate, or malic acid, is found in fruits such as apples and enhances the effects of citrulline. Malic acid takes part in aerobic cellular respiration where oxygen and a carbon compound (acetyl Co-A) are used to produce immediate energy and CO2 in the mitochondria of the cell. This is called the Krebs cycle. Malate conditions the recycling of lactate and pyruvate promoting efficient energy production and protecting muscles from fatigue. Citrulline malate improves aerobic performance and capacity by influencing lactic acid metabolism and reducing fatigue. Citrulline's functions stem primarily from its ability to increase plasma levels of Arginine endogenously (in the human body) Citrulline increases plasma Arginine levels better than taking the amino acid Arginine itself.
BETA-ALANINE: is a naturally occurring beta amino acid . B-Alanine is the rate-limiting precursor of carnosine, which is to say carnosine levels are limited by the amount of available B-alanine. Supplementation with B-alanine has been shown to increase the concentration of carnosine in muscles, decrease fatigue in athletes and increase total muscular work done. Carnosine (beta-alanyl-L-histidine) is a di-peptide composed of the amino acids beta alanine and histidine. It buffers H+ (acid) and is needed for muscles to function properly during intense exercise. Specifically it must be present to maintain intracellular pH. Originally, supplemental carnosine was touted to increase carnosine levels. Later it was discovered carnosine was not being absorbed in its native state, rather it was beta alanine that was needed to increase carnosine levels. Many companies add L-histidine, but it is not necessary as the body has plenty to spare.
SUGGESTED USE As a dietary supplement take 2 scoopfuls (25g) 30-45 minutes before intense physical activity such as weight training. Females and males under 150lbs ½ serving may prove optimal. Compound can be mixed in any liquid or taken straight with any liquid, such as water, sugar free drinks, and low to no calorie rehydrating sports drinks. Highly glycemic sugars (like those taken with creatine such as fruit juices that contain simple sugars such as glucose or dextrose) should be avoided prior to exercise because of the sudden crash in energy levels they cause.
Option 2: Take ½ serving 30-45 minutes prior to intense physical activity and ½ serving immediately following. Adhering to the same ingestion protocol listed above.
CREATINE BASED SUPPLEMENTS: This product was designed to be a performance enhancer during intense physical activity such as weight training but can be used as a sole creatine product. If using it for such purposes the best time to take creatine is immediately after your workout when the metabolic state of skeletal muscle is most receptive to insulin-mediated uptake of creatine. You may even Further capitalize on this situation by taking creatine with fruit juices (at least 16 ounces) that contain simple sugars such as glucose or dextrose. The more glycemic the sugar the more creatine is absorbed by the human skeletal muscle system. With this being scientifically stated we lose the benefits of our other compounds during our training and physical activity sessions, but gain their advantages in our post anabolic state following our training or activity sessions. Experiment with different times taking product, before, after and even both to find out which method works best for you.
While using A creatine based supplement, make sure to consume plenty of water daily to avoid dehydration. 128 oz or more daily is optimal during creatine use.
WARNING: Consult your physician before using this product if you are diabetic, liver or kidney disease, following a heart attack or history of heart disease, herpes (arginine does not "cause" a herpes outbreak but rather it exacerbates the replication of the virus of an impending or an active outbreak), if using ACE inhibitors and potassium sparing diuretics, pregnant, nursing or taking any medications. Do not use this product.
*These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The FDA does not evaluate or regulate any dietary supplements .Make an educated decision when purchasing dietary products.
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