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Ephedrology; how does ephedra do it?

MA HUANG MYSTERIES
HOW DOES IT DO IT?


Similar to the structurally related drug amphetamine, ephedrine directly stimulates the central nervous system (CNS) by increasing the amount of the neurotransmitter dopamine that is present in the body. This interaction, considered a dopamine agonist, results in a suppression of appetite, increased myocardial contraction and heart rate which contributes to thermogenesis or burning of calories for fuel and is part of increasing metabolism, peripheral vasoconstriction, as is seen with “fight or flight” reactions induced by adrenal glands, and simulates mydriasis, or enlarged pupils, a property that is seen with high concentrations of norepinephrine and epinephrine and therefore an increase in adrenergic neurotransmission. The result is a fine tuned focus, energy, and appetite suppressant. This type of effect is utilized with many ADHD medications, aiding in focus and alertness, and with weight loss medications reserved for obese individuals. Ephedrine is also an effective herbal alkaloid stimulant of a low functioning Sympathetic Nervous System (SNS) to which obesity may be connected.

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